PRESCRIBED MIGRAINE TREATMENT IN ITS CLASS

SINCE 08/06/21

Why Nurtec ODT?

Relief for today.
Prevention for the future.

Only Nurtec ODT can be used to treat or help prevent migraine

Works as soon as 2 hours

and lasts up to 2 days

treat migraine attacks

Reduce monthly migraine days

when taken every other day

help prevent migraine attacks

The only dissolvable tablet

so no water is necessary

taking Nurtec ODT

The safety of using more than 18 doses in a 30-day period has not been established. You should not take more than 1 tablet in 24 hours.

Per IQVIA as brand in class (oral CGRP receptor antagonists): number one prescribed and in new prescriptions since 8/6/21. Current as of February 2025.

I’m a 32-year-old mom of 2 and I can’t function with a migraine attack, so it’s helpful for me that Nurtec ODT can provide relief.

Jenna B

Actual Nurtec ODT Patient

Treat migraine attacks
with one quick-dissolving tablet

When migraine interrupts, take back your time.

At 2 hours, people taking Nurtec ODT experienced the following‡:

Pain relief

  • 59.3% of people taking Nurtec ODT experienced pain relief (vs 43.3% with placebo)
  • For some, pain relief lasted up to 48 hours

Pain freedom & freedom from most bothersome symptom

  • 21.2% of people taking Nurtec ODT experienced pain freedom (vs 10.9% with placebo)
  • 35.1% of people taking Nurtec ODT experienced freedom from their most bothersome symptom (light sensitivity, sound sensitivity, or nausea) vs 26.8% with placebo

Return to normal activity

  • 38.1% of people taking Nurtec ODT returned to normal function (vs 25.8% with placebo)

Within 24 hours‡:

Most people didn't need additional medication

  • After 1 dose of Nurtec ODT, 86% of people did not use a rescue medication (vs 71% with placebo)

In a study of 669 people taking Nurtec ODT for the acute treatment of migraine attacks vs 682 people taking placebo.

Help prevent migraine attacks with one quick-dissolving tablet.

Migraine can be unpredictable—and you don’t have time for that.

People taking Nurtec ODT every other day experienced the following at 12 weeks§:

Significant reduction in monthly migraine days (MMDs)

  • People taking Nurtec ODT experienced 4.3 fewer MMDs during weeks 9–12 (vs 3.5 fewer MMDs with placebo)

Monthly migraine days cut in half

  • Almost 50% of people saw their days with moderate-to-severe headache pain intensity cut in half with Nurtec ODT vs 41.5% with placebo.

§In a study of 348 people taking Nurtec ODT every other day for the preventive treatment of migraine attacks vs 347 people taking placebo.

Take Nurtec ODT wherever you are

You can take Nurtec ODT as soon as symptoms begin to stop migraine attacks or every other day to prevent them—because with migraine, you don’t have time to wait.

One tablet that dissolves in seconds with no water needed||

||Do not take more than one tablet of Nurtec ODT in 24 hours. The safety of using more than 18 doses in a 30-day period has not been established.

Store Nurtec ODT in the blister package that it comes in. Store Nurtec ODT at room temperature between 68°F to 77°F (20°C to 25°C).

A newer type of migraine treatment

Nurtec ODT targets and blocks CGRP (calcitonin gene-related peptide), a protein in the brain believed to be a key cause of migraine attacks.

DURING A MIGRAINE

A protein called CGRP is released during migraine attacks.

DURING A MIGRAINE

CGRP attaches to receptors, causing nerve inflammation and increased pain signals to the brain.

HOW NURTEC ODT WORKS

Nurtec ODT works by helping block CGRP receptors.

HOW NURTEC ODT WORKS

This prevents CGRP from binding to the receptors, which can help treat and prevent migraine attacks.